Thursday, December 20, 2012

Integumentary System!

The Integumentary System better known as skin consists of three or more mayor regions. You're skin actually goes a lot deeper than you think. The three regions of the skin are the epidermis, dermis, and hypodermis. The epidermis is the outermost superficial region, the dermis is the middle region, and the hypodermis  is the deepest region of the skin. 

The epidermis is composed of keratinized stratified squamos epithelium, that consists of four different cell types and four of five layers. The cell types include kerationocytes, melanocytes, Merkel cels, and Langerhan's cells. The outer portion of the skin is exposed to the external environment and functions in protection. Since the epidermis is the top layer of skin, you shed skin every day without even knowing it! In the epidermis, there are different layers within it. The first is the Stratum Basale layer, usually just known as the Basal layer. It is the deepest epidermal layer, attached firmly to the dermis, and also consists of a single row of the youngest keratinocytes. The cells in the Basal Layer undergo rapid division. The next layer in the epidermis is the Stratum Spinosum, a.k.a the Prickly Layer. The cells in this layer have a weblike system of intermediate filaments attached to desmosomes. Melanin granules and Langerhans' cells are really big in this layer. The layer after that is the Stratum Granulosum (Granular Layer). This layer is a very thin layer that has three to five cell layers in which major changes in keratinocyte appearance happens. Keratohyaline and lamellated granules build up in the cells of this layer. Next is the Stratum Lucidum a.k.a as the clear layer. This layer is a very thin, transparent band superficial to the stratum granulosum. It is a few rows of dead, flat keratinocytes. It is only present in thick skin. The last layer of the epidermis is the Stratum Corneum a.k.a the Horny Layer, yes i know that is a funny name. This layer is the outermost layer of keratinized cells, and it accounts for three quarters of the thickness of the epidermis. It's functions include: protection from abrasion and penetration, waterproofing, and rendering the body relatively insensitive to biological, chemical, and physical assaults.
     The next major layer below the epidermis is the Dermis that has strong, and flexible connective tissue. The cels in this layer include fibroblasts, macrophages, and sometimes have mast cells and white blood cells. This layer consists of two layers, papillary and reticular. The papillary layer has Areolar connective tissue with collagen and elastic fibers. Its surface has peg like projections called dermal papillae. Dermal papillae contains capillary loops, Meissner's corpuscles, and free nerve endings. The reticular layer accounts for about 80% of the thickness of the skin, and has collagen fibers that add strength and resiliency to the skin. Elastin fibers provide stretch-recoil properties.
     The Hypodermis is the deepest layer of your skin, and it is composed of adipose and areolar connective tissue.

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